Failing to find a doctor capable of treating their young son Lorenzo's rare disease, Augusto and Michaela Odone seek their own cure. They set out on a mission to find a treatment and save their child. In their quest for a treatment the Odones clash with doctors, scientists, and support groups, who are skeptical that anything could be done about ALD, much less by laypeople. But they persist, setting up camp in medical libraries, reviewing animal experiments, badgering researchers, questioning top doctors all over the world, and even organizing an international symposium about the disease. Despite dead ends of research, the horror of watching their son's health decline, and being surrounded by skeptics (including the coordinators of the support group they attend), they persist until they finally hit upon a therapy involving adding a certain kind of oil (actually olive oil with two specific long chain fatty acids removed) to their son's diet. They contact over 100 firms around the world until they find an elderly British chemist working for Croda International who is willing to take on the challenge of distilling the proper formula. It proves successful in normalizing the accumulation of the very long chain fatty acids in the brain that have been causing their son's steady decline, thereby halting the progression of the disease. There is still a great deal of neurological damage remaining which cannot be reversed until new treatments are found to regenerate the myelin sheath (a lipid insulator) around the nerves.
The film ends with Lorenzo at the age of 14 showing definite improvement (he can swallow for himself and answer yes or no questions by blinking) but indicating more medical research is still needed. The end credits of the film say that Lorenzo also regained his sight and was learning to use a computer. Many healthy children are shown who, having followed a course of treatment with Lorenzo's oil, have remained symptom-free. Lorenzo can communicate again via a modified sign language, and that Augusto Odone later received an honorary M.D. for his pioneering work in researching and discovering a significant treatment for ALD.
As I watched this movie I thought, why? Why did God allow this child, this family to endure such pain and suffering? And I don't mean why as in...Oh God why them, they were so good, why not someone else? I didn't mean it in that way at all. I meant, there must be a reason God chose them. Just the way he allowed Job to endure the trials satan chose to inflict on him. I believe that God is so good and wise, He made each of us, He knows what circumstances will motivate us to be our best and to live our purpose, even when we don't. I thought wow, God is so remarkable that He knew even before this kid (Lorenzo Odone) was born, how his parents would fight for his life. In fact I believe that He paired these parents together because of their own unique and remarkable traits. His father for his scientific background and his mother for her unrelenting passion and persistence. I believe that God allowed this to happen to them for the greater good of all the other boys in the world with this awful disease. For the boys whose parents didn't have the education, resources, will or patience to help find a cure. Today because of their determination and faith, thousands, maybe even hundreds of thousands of children and their families are spared from this debilitating disease.
So when I think about all of the ordeals that I have suffered in my life, oddly enough, I praise God for His wisdom and His Omniscience. He knows exactly what circumstances to allow in our lives to spur us on to be the best that we can be. He knows how to nudge us onto the path to our purpose. While I'm going through bad times I'm not necessarily skipping and jumping for j0y, but I try to remind myself to count it all joy, because the God that I Love, and trust, the God whose only intention is for good in my life, is pushing me to reach my full potential. He is refining us like silver. Challenging us to turn our Grief into Greatness. But only He knows exactly what will motivate and inspire each one of us to our own individual revelations to change our lives and the lives of those around us.